2-Methylindole → HCID 20442785, compound

HRID 544784Notes

Reaction equation

[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([C:13](=O)[C:14]([Cl:20])=[C:15]([Cl:19])[C:16]([OH:18])=[O:17])=[C:5]1[CH3:22])[CH:2]=[CH2:3].[CH2:23]([N:29]1[C:37]2[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=2)[CH:31]=[CH:30]1)[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].CC1NC2C(C=1)=CC=CC=2>>[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([C:13]2([C:31]3[C:32]4[C:37](=[CH:36][CH:35]=[CH:34][CH:33]=4)[N:29]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:30]=3)[O:18][C:16](=[O:17])[C:15]([Cl:19])=[C:14]2[Cl:20])=[C:5]1[CH3:22])[CH:2]=[CH2:3]

Participants

Reactant 3

HCID 72242-Methylindole

HCID 127154041-Hexyl-1H-indole

HCID 54009122HCID 54009122, compound

Product 1

HCID 20442785HCID 20442785, compound

Procedure

Following a procedure similar to that described above in part B of this example except that 4-(1-allyl-2-methyl-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid is used in place of 4-(1-ethyl-2-methyl-3-indolyl)-2,3-dichloro-4-oxo-2-butenoic acid and 1-n-hexylindole is substituted for 2-methylindole, there is obtained 5-(1-allyl-2-methyl-3-indolyl)-5-(1-n-hexyl-3-indolyl)-3,4-dichloro-2(5H)-furanone (Formula V: R=CH2 =CHCH2 ; R1 =CH3 ; R2 =CH3 (CH2)4CH2 ; R3 =Y=Y1 =H).

Sources & evidence

ORD record: ord-406ada54d72e493c9ab7a07b552318a1
Source dataset: uspto-grants-1984_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04451657

Reaction notes

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