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HRID544934

反应详情

EQUATION

反应方程式

HRID 544934 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1cccnc1
HCID2734378

3-Pyridinylboronic acid

C5H6BNO2

结构：Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1scc(Br)c1C
HCID59761512

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1scc(-c2cccnc2)c1C
HCID24985753

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by coupling 4-bromo-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl)-3-methylthiophene-2-carboxamide with commercially available 3-pyridylboronic acid using the method described in Step B of Example 136 to afford a white solid (Example 198). HPLC Ret time=1.98 min. LCMS [M+H]+ 392.29.

WORKUP

后处理

  1. customto afford a white solid (Example 198)
  2. customHPLC Ret time=1.98 min