化工社化工社 化学情報印刷レポート · 研究参考用
Nitric Acid → HCID 178526837、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Nitric Acid | HCID 944 | — |
| 反応物 | 2(1H)-Pyridinone, 3-(trifluoromethyl)- | HCID 3678411 | — |
| 溶媒 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | HCID 178526837 | HCID 178526837 | — |
反応手順
To 3-trifluoromethyl-pyridin-2-ol (1.63 g, 10 mmol) in concentrated sulfuric acid at 0° C., add dropwise fuming nitric acid (2 mL). Stir the mixture at room temperature for 3 hours and pour onto ice. Collect the precipitate by filtration, air-dry and finally dry in a vacuum oven overnight to give the title compound as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07935702B2 |
| 出典データセット | uspto-grants-2011_05 |
| ORD ID | ord-42451f0e310d4e8eaf391acfbea031e5 |
| 出典メモ | uspto-grants-2011_05 |