HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → (S)-2-Phenyl-2-(1H-imidazol-1-yl)-1-aminoethane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | HCID 11018848 | HCID 11018848 | — |
| Product | (S)-2-Phenyl-2-(1H-imidazol-1-yl)-1-aminoethane | HCID 53732650 | — |
Reaction Steps
1 g of (R)(-)-2-phenyl-aziridine and 1.14 g of imidazole are heated at 120° for 24 hours. After cooling the reaction mixture can be used for the acylating step without further purification. An analytical sample can be obtained by chromatography over silica gel;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05622982 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-ac94eab7979440e8ae1d0bd0f8ff29ec |
| Source note | uspto-grants-1997_04 |