反应详情

A mixture of N-[2-[1-tert-butoxycarbonylpiperidin-4-yl]ethyl]phthalimide (1.0 g) and hydrazine hydrate (0.16 ml) in ethanol (10 ml) was refluxed for 1 hour. After cooling to room temperature, the mixture was evaporated. The residue was chromatographed on alumina eluting with chloroform and the fractions containing the object product were collected and evaporated to give 2-[1-tert-butoxycarbonylpiperidin-4-yl]ethylamine (0.4 g) as an oil.

1. temperaturewas refluxed for 1 hour
2. customthe mixture was evaporated
3. customThe residue was chromatographed on alumina eluting with chloroform
4. additionthe fractions containing the object product
5. customwere collected
6. customevaporated