HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Bromo-2-fluorophenyl)hydrazine → N-(6-Bromo-8-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)-isobutyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Bromo-2-fluorophenyl)hydrazine | HCID 609902 | — |
| Reactant | 2-Methyl-N-(4-oxocyclohexyl)propanamide | HCID 21533994 | — |
| Product | N-(6-Bromo-8-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)-isobutyramide | HCID 57431654 | 32% |
Reaction Steps
Prepare the tide compound by essentially following the procedure as described in Preparation 4 (Method 2) with 2-fluoro-4-bromophenylhydrazine (Preparation 14) and N-(4-oxo-cyclohexyl)-isobutyramide, to obtain the title compound as a tan foam in 32% yield. MS (ES): m/z 353, 355 (M+H), 351, 353(M−H); HPLC (Method A): Rt=2.34, (89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935722B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-09008142521b4e6db4f3215ac170eea5 |
| Source note | uspto-grants-2011_05 |