HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azobisisobutyronitrile → HCID 18442815, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 5-Methylthiazole | HCID 137980 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 18442815 | HCID 18442815 | 49.1% |
| Product | 5-(Bromomethyl)-1,3-thiazole | HCID 21698401 | — |
Reaction Steps
An N,N-dimethylformamide solution of 5-(bromo-methyl)thiazole was prepared by using 5-methylthiazole (5.00 g), N-bromosuccinimide (8.97 g) and α,α′-azobisisobutyronitrile (414 mg) in a similar manner to Referential Example 86, and morpholine (2.20 ml) and triethylamine (7.02 ml) were reacted with this solution to obtain the title compound (1.76 g) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07935824B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-3d307f9cfddc431e96da024d6cf753e3 |
| Source note | uspto-grants-2011_05 |