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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 546525Generated: November 1, 2026

Hydrochloric Acid → HCID 58822086, compound

https://huagongshe.com/reaction/546525

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantLithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylateHCID 23704331—
ReactantHCID 58822090HCID 58822090—
SolventEthanolHCID 702—
ProductHCID 58822086HCID 58822086—

Reaction Steps

(1R*,2S*,4S*)-N1-tert-Butoxycarbonyl-N2-[(5-chloroindol-2-yl)carbonyl]-4-methoxycarbonyl-1,2-cyclohexanediamine was treated with a saturated ethanol solution of hydrochloric acid and then condensed with lithium 5-methyl-4,5,6,7-tetrahydro-thiazolo[5,4-c]-pyridine-2-carboxylate in a similar manner to Example 118 to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07935824B2
Source datasetuspto-grants-2011_05
ORD IDord-f08be433e2094336b93ed5c134fc629d
Source noteuspto-grants-2011_05