Sodium Carbonate → HCID 3265106, compound

HRID 54694Notes

Reaction equation

HRID 54694 reaction equation
[NH2:1][C:2]1[N:3]([CH2:17][C:18](=O)[C:19]([CH3:22])([CH3:21])[CH3:20])[C:4]2[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=2[N+:6]=1[CH2:7][CH2:8][CH2:9][N:10]([CH3:12])[CH3:11].C(=O)([O-])[O-].[Na+].[Na+]>C(O)C>[C:19]([C:18]1[N:1]=[C:2]2[N:3]([CH:17]=1)[C:4]1[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=1[N:6]2[CH2:7][CH2:8][CH2:9][N:10]([CH3:12])[CH3:11])([CH3:22])([CH3:21])[CH3:20]

Participants

4

Reactant 2

HCID 10340Sodium CarbonateHCID 178483518HCID 178483518, compound

Product 1

HCID 3265106HCID 3265106, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Heat at reflux for 25 minutes 3 mmol of the hydrobromide obtained in Step A and 4 g of sodium carbonate in 25 ml of ethanol. Evaporate, treat the residue twice with 10 ml of chloroform each time, and pass the resulting chloroform solutions over a column of alumina. Evaporate the eluate. The title compound is obtained in the form of an oil.

Workup

  1. temperatureHeat
  2. customEvaporate
  3. additiontreat the residue twice with 10 ml of chloroform each time
  4. customEvaporate the eluate

Sources & evidence

ORD record
ord-f5081583cf91431da358561f1507debe
Source dataset
uspto-grants-1997_04
Patent number
US05623073

Reaction notes

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