反应详情

Add 1.04 ml (10 mmol) of diethylamine to a hot solution of 9-benzyl-2-bromomethyl-3-ethoxycarbonylimidazo[1,2-a]benzimidazole (2.01 g, 5 mmol), prepared as described for the alkylated analogues in Khim. Farm. ZH 88, 22 (7), 815-9, in 20 ml of benzene. Heat at reflux for one hour, cool. Remove the resulting precipitate, evaporate the benzene, and the residue is recrystallised by hexane to yield the title compound.

1. customprepared
2. temperatureHeat
3. temperatureat reflux for one hour
4. temperaturecool
5. customRemove the resulting precipitate
6. customevaporate the benzene
7. customthe residue is recrystallised by hexane