Hydrochloric Acid → 2-Methyl-9-(2-morpholinoethyl)-3-(4-chlorobenzoyl)imidazo[1,2-a]benzimidazole dihydrochloride

HRID 54702Notes

Reaction equation

HRID 54702 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]2[N:8]([C:9]=1[C:10](=[O:18])[C:11]1[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=1)[C:7]1[CH:19]=[CH:20][CH:21]=[CH:22][C:6]=1[N:5]2[CH2:23][CH2:24][N:25]1[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1.[ClH:31]>CC(C)=O>[ClH:17].[ClH:31].[CH3:1][C:2]1[N:3]=[C:4]2[N:8]([C:9]=1[C:10](=[O:18])[C:11]1[CH:12]=[CH:13][C:14]([Cl:17])=[CH:15][CH:16]=1)[C:7]1[CH:19]=[CH:20][CH:21]=[CH:22][C:6]=1[N:5]2[CH2:23][CH2:24][N:25]1[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 129658422-Methyl-9-(2-morpholinoethyl)-3-(4-chlorobenzoyl)imidazo[1,2-a]benzimidazole

Product 1

HCID 190408112-Methyl-9-(2-morpholinoethyl)-3-(4-chlorobenzoyl)imidazo[1,2-a]benzimidazole dihydrochloride

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

1.7 g of the base obtained in Step B is dissolved in 30 ml of acetone and acidified with concentrated hydrochloric acid: the title compound precipitate is removed by filtration and recrystallised from ethanol.

Workup

  1. customthe title compound precipitate is removed by filtration
  2. customrecrystallised from ethanol

Sources & evidence

ORD record
ord-6e8613bf52764e1184f6c7e52d9294ec
Source dataset
uspto-grants-1997_04
Patent number
US05623073

Reaction notes

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