Hydrochloric Acid → 10-Phenacyl-2,3,4,10-tetrahydropyrimidino[1,2-a]benzimidazole hydrochloride

HRID 54706Notes

Reaction equation

HRID 54706 reaction equation
[CH2:1]([N:10]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]2[CH2:19][CH2:20][CH2:21][N:22]=[C:11]12)[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[O:3].[ClH:23]>CC(C)=O>[ClH:23].[CH2:1]([N:10]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]2[CH2:19][CH2:20][CH2:21][N:22]=[C:11]12)[C:2]([C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1)=[O:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 791781HCID 791781, compound

Product 1

HCID 4488926310-Phenacyl-2,3,4,10-tetrahydropyrimidino[1,2-a]benzimidazole hydrochloride

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The compound obtained in Step C is dissolved in acetone. The solution obtained is treated with concentrated hydrochloric acid. Suction-filter the precipitate and recrystallise from ethanol.

Workup

  1. customThe solution obtained
  2. filtrationSuction-filter the precipitate
  3. customrecrystallise from ethanol

Sources & evidence

ORD record
ord-351a4862d0c74300aa0a29ea503c2b60
Source dataset
uspto-grants-1997_04
Patent number
US05623073

Reaction notes

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