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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 54707Generated: October 30, 2026

Hydrochloric Acid → 10-[2-Hydroxy-2-(4-chlorophenyl)ethyl]-2,3,4,10-tetrahydropyrimidino[1,2-a]benzimidazole hydrochloride

https://huagongshe.com/reaction/54707

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1-(4-chlorophenyl)-2-(3,4-dihydropyrimido[1,2-a]benzimidazol-10(2H)-yl)ethanolHCID 2899765—
SolventIsopropanolHCID 3776—
Product10-[2-Hydroxy-2-(4-chlorophenyl)ethyl]-2,3,4,10-tetrahydropyrimidino[1,2-a]benzimidazole hydrochlorideHCID 2899764—

Reaction Steps

Slowly add isopropanolic hydrogen chloride to an isopropanol solution of the base obtained in Step A. Wait for 30 minutes. Suction-filter, and wash with acetone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05623073
Source datasetuspto-grants-1997_04
ORD IDord-0abcd3d5c3e549099ebe9ca4ca331704
Source noteuspto-grants-1997_04