Sodium Hydroxide → HCID 57443585, compound

Participants

Reaction Steps

A 0.25 N sodium hydroxide aqueous solution (0.060 mL) was added to a solution of [6-(4-{1-ethyl-1-[4-(3-hydroxy-4,4-dimethyl-pentyl)-3-methyl-phenyl]-propyl}-2-methyl-phenyl)-pyridazin-4-yl]acetic acid ethyl ester (Example 183-(4); 6.5 mg, 0.012 mmol) in methanol (0.20 mL) at room temperature, and the mixture was stirred at room temperature for four hours. The reaction mixture was concentrated under reduced pressure to give the title compound (6.5 mg, 100%).

Provenance & Evidence