HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,4-Trifluoro-3-butene-1-amine → HCID 178518876, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,4-Trifluoro-3-butene-1-amine | HCID 15239145 | — |
| Reactant | 4,5-dihydro-5-oxo-1H-pyrazole-4-carboxaldehyde | HCID 19704272 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178518876 | HCID 178518876 | 68% |
Reaction Steps
A solution of 3,4,4-trifluoro-3-butene-1-amine (2.25 g, 0. 018 mole) and 4,5-dihydro-5-oxo-1H-pyrazole-4-carboxaldehyde (1.12 g 0.01 mole) in absolute ethanol (30 mL) is heated at reflux for 15 min. The solution is concentrated and the residue is recrystallized from ether/dichloromethane to give 1.49 g of the title compound as an yellow solid, a 68% yield. m.p. 126°-130° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623084 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-cd8187dee18548c380566a3e69ea8aaa |
| Source note | uspto-grants-1997_04 |