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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 547476Generated: October 31, 2026

HCID 67201906, compound → HCID 44193195, compound

https://huagongshe.com/reaction/547476

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67201906HCID 67201906—
SolventMethanolHCID 887—
ProductHCID 44193195HCID 44193195—

Reaction Steps

1-{2-[1-(2-Hydroxy-ethyl)-1H-indol-3-yl]-5H-pyrrolo[2,3-b]pyrazin-7-yl}-2,2-dimethyl-propan-1-one was prepared following the same procedure but using 1-[2-{1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1H-indol-3-yl}-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one as starting material. The product was obtained in 67% by trituration in MeOH.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07939531B2
Source datasetuspto-grants-2011_05
ORD IDord-e279fe62c20f4c2884e1b0fc5ad776e9
Source noteuspto-grants-2011_05