HCID 67203342, compound → HCID 57829614, compound

Participants

Reaction Steps

2,2-Dimethyl-1-(2-{1-[2-(4-methyl-piperazin-1-yl)-ethyl]-1H-indol-3-yl}-5H-pyrrolo[2,3-b]pyrazin-7-yl)-propan-1-one was prepared following a similar procedure but using 2,2-dimethyl-1-[2-{1-[2-(4-methyl-piperazin-1-yl)-ethyl]-1H-indol-3-yl}-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-propan-1-one as starting material. The product was isolated in 75% yield by SiO2 chromatography (DCM/[DCM/MeOH/NH4OH 60/10/1] 100-75% DCM).

Provenance & Evidence