Water → HCID 131719986, compound

HRID 54769Notes

Reaction equation

HRID 54769 reaction equation
[N+](C1C=CC(C[O:11][C:12]([C:14]2[N:15]3[CH:18]([CH:19]([CH3:35])[C:20]=2[S:21][CH:22]2[CH2:26][CH:25]([CH2:27][O:28][C:29]4[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=4)[O:24][CH2:23]2)[CH:17]([CH:36]([OH:38])[CH3:37])[C:16]3=[O:39])=[O:13])=CC=1)([O-])=O.C(=O)(O)[O-].[Na+:44].O>[Pd].O1CCOCC1>[Na+:44].[OH:38][CH:36]([CH:17]1[C:16](=[O:39])[N:15]2[CH:18]1[CH:19]([CH3:35])[C:20]([S:21][CH:22]1[CH2:26][CH:25]([CH2:27][O:28][C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[O:24][CH2:23]1)=[C:14]2[C:12]([O-:13])=[O:11])[CH3:37]

Participants

6

Reactant 3

HCID 962WaterHCID 516892Sodium BicarbonateHCID 131719988HCID 131719988, compound

Product 1

HCID 131719986HCID 131719986, compoundYield 20.4%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 312751,4-DioxaneSolvent

Procedure

The title compound is prepared by the procedure of Example 18 using 0.320 g of product from Example 25, 0.054 g of sodium bicarbonate, 3.5 ml of water, 8.3 ml of dioxane and 0.166 g of 10% palladium/carbon to give 0.052 g of the desired product.

Sources & evidence

ORD record
ord-29230e4547a24481bad81faf5ef3b3f2
Source dataset
uspto-grants-1997_04
Patent number
US05623081

Reaction notes

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