HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 5-[(4-Fluorophenoxy)methyl]tetrahydro-3-furanthiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Ethanethioic acid trans-(+/-)-S-[5-[(4-fluorophenoxy)methyl]tetrahydro-3-furanyl]ester | HCID 86750320 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-[(4-Fluorophenoxy)methyl]tetrahydro-3-furanthiol | HCID 18924004 | 52.4% |
Reaction Steps
The title compound is prepared by the procedure of Example 16 using 0.943 g of product from Example 35, 0.86 ml of 25% .sodium methhoxide/methyl alcohol and 12 ml of tetrahydrofuran to give 0.417 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05623081 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-3ce85b28e88b461fa73e7fec6b5c1517 |
| Source note | uspto-grants-1997_04 |