Water → HCID 131719989, compound

HRID 54775Notes

Reaction equation

HRID 54775 reaction equation
[N+](C1C=CC(C[O:11][C:12]([C:14]2[N:15]3[CH:18]([CH:19]([CH3:36])[C:20]=2[S:21][CH:22]2[CH2:26][CH:25]([CH2:27][S:28][C:29]4[CH:34]=[CH:33][C:32]([F:35])=[CH:31][CH:30]=4)[O:24][CH2:23]2)[CH:17]([CH:37]([OH:39])[CH3:38])[C:16]3=[O:40])=[O:13])=CC=1)([O-])=O.C(=O)(O)[O-].[Na+:45].O>[Pd].O1CCOCC1>[Na+:45].[F:35][C:32]1[CH:33]=[CH:34][C:29]([S:28][CH2:27][CH:25]2[O:24][CH2:23][CH:22]([S:21][C:20]3[CH:19]([CH3:36])[CH:18]4[N:15]([C:16](=[O:40])[CH:17]4[CH:37]([OH:39])[CH3:38])[C:14]=3[C:12]([O-:13])=[O:11])[CH2:26]2)=[CH:30][CH:31]=1

Participants

6

Reactant 3

HCID 962WaterHCID 516892Sodium BicarbonateHCID 131719991HCID 131719991, compound

Product 1

HCID 131719989HCID 131719989, compoundYield 33.4%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 312751,4-DioxaneSolvent

Procedure

The title compound is prepared by the procedure of Example 18 using 0.230 g of product from Example 41, 0.118 g of 10% palladium/carbon, 0.038 g of sodium bicarbonate, 2.5 ml of water and 6.0 ml of dioxane to give 0.062 g of the desired product.

Sources & evidence

ORD record
ord-93ebdeae058f44f4957553ad417c4167
Source dataset
uspto-grants-1997_04
Patent number
US05623081

Reaction notes

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