Hydrochloric Acid → HCID 67195616, compound

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Reaction Steps

A solution of 4-(6-amino-5-methyl-pyridin-3-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (2.84 g, 9.27 mmol) in dioxane (30 mL) and 4 M HCl in dioxane (20 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 207.1 [M+H]+.

Provenance & Evidence