HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67194713, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 67196123 | HCID 67196123 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67194713 | HCID 67194713 | — |
Reaction Steps
A solution of 4-(2-methyl-pyridin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (1.31 g, 4.50 mmol) in dioxane (20 mL) and 4 M HCl in dioxane (20 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 192.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07939661B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-529d928633c046148df89fc8a92a9f17 |
| Source note | uspto-grants-2011_05 |