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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 547907Generated: October 31, 2026

Hydrochloric Acid → HCID 67194713, compound

https://huagongshe.com/reaction/547907

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 67196123HCID 67196123—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 67194713HCID 67194713—

Reaction Steps

A solution of 4-(2-methyl-pyridin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (1.31 g, 4.50 mmol) in dioxane (20 mL) and 4 M HCl in dioxane (20 mL) was stirred at rt for 2 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 192.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07939661B2
Source datasetuspto-grants-2011_05
ORD IDord-529d928633c046148df89fc8a92a9f17
Source noteuspto-grants-2011_05