Citric Acid → HCID 131728835, compound

Participants

Reaction Steps

Before filling into hard gelatine capsules, 2500 g of the thus obtained lacquered active agent pellets were screened under addition of 15 g microfine talc. The particle size fraction of 0.7 mm to 1.25 mm (2450 g, corresponding to 98.0% of the theoretical amount) has a content of 18.5% of propiverine-hydrochloride as determined according to Example 6. The content of citric acid was determined by means of the titration as described in Example 6 to be 49%. Thus the result is a molar ratio of propiverine to citric acid of 1:5.6, which is in the typical range.

Provenance & Evidence