反应详情

To a solution of (4-hydroxy-2-methyl-phenoxy)-acetic acid methyl ester (5.1 g, 25.8 mmol) and K2CO3 (7.1 g, 51.5 mmol) in acetone (85 ml) was added propagylbromide (3.1 g, 25.7 mmol) at room temperature. The reaction mixture was stirred at room temperature for 2 days, and then filtered and evaporated in vacuo. The residue was purified on column chromatography using methylene chloride as eluent to give the title compound in 6.0 (100%) yield.

1. filtrationfiltered
2. customevaporated in vacuo
3. customThe residue was purified on column chromatography