HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,6-Dibromopyridazine → 3-Bromo-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,6-Dibromopyridazine | HCID 248852 | — |
| Reactant | (5-Methyl-3-phenyl-1,2-oxazol-4-yl)methanol | HCID 2776149 | — |
| Product | 3-Bromo-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridazine | HCID 42629653 | 89% |
Reaction Steps
As described for example 1, (5-methyl-3-phenyl-isoxazol-4-yl)-methanol (2.46 g, 13 mmol) was converted using 3,6-dibromopyridazine instead of 3,6-dichloropyridazine to the title compound (3.99 g, 89%) as a white solid. MS: m/e=348.0/346.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943619B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-883c77a502ba472a9efb879101a353a1 |
| Source note | uspto-grants-2011_05 |