Ethanamine, 2,2,2-trifluoro- → HCID 67157620, compound

Participants

Reaction Steps

As described for example 52, 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridazine-3-carboxylic acid ethyl ester (143 mg, 0.4 mmol) was converted, using 2,2,2-trifluoroethylamine instead of ethanolamine, to the title compound (127 mg, 77%) which was obtained as an off-white solid. MS: m/e=411.1 [M+H]+.

Provenance & Evidence