Isopropylamine → HCID 42629535, compound

Participants

Reaction Steps

As described for example 52, 6-[3-(3-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridazine-3-carboxylic acid ethyl ester (143 mg, 0.4 mmol) was converted, using isopropylamine instead of ethanolamine, to the title compound (58 mg, 39%) which was obtained as a white solid after recrystallisation from heptane:ethyl acetate. MS: m/e=371.0 [M+H]+.

Provenance & Evidence