Thiomorpholine → HCID 67158094, compound

Participants

Reaction Steps

As described for example 59, 6-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridazine-3-carboxylic acid ethyl ester (143 mg, 0.4 mmol) was converted, using thiomorpholine instead of aminomethylcyclopropane, to the title compound (140 mg, 85%) which was obtained as an off-white solid. MS: m/e=415.4 [M+H]+.

Provenance & Evidence