HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 5-methyl-3-pyridin-4-ylisoxazole-4-carboxylate → (5-Methyl-3-pyridin-2-yl-isoxazol-4-yl)-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 5-methyl-3-pyridin-4-ylisoxazole-4-carboxylate | HCID 22137723 | — |
| Reactant | HCID 22309063 | HCID 22309063 | — |
| Product | (5-Methyl-3-pyridin-2-yl-isoxazol-4-yl)-methanol | HCID 66643722 | 97% |
Reaction Steps
As described for example 67b, 5-methyl-3-pyridin-2-yl-isoxazole-4-carboxylic acid ethyl ester (25 g, 108 mmol) was converted, instead of 5-methyl-3-pyridin-4-yl-isoxazole-4-carboxylic acid ethyl ester, to the title compound (19.8 g, 97%) which was obtained as a light yellow solid. MS: m/e=191.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943619B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-fd7fae926a564b38ad959ea6c27fb0a3 |
| Source note | uspto-grants-2011_05 |