HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67157711, compound → HCID 67157274, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67157711 | HCID 67157711 | — |
| Reactant | 2-[3-(4-Fluoro-phenyl)-5-methyl-isoxazol-4-ylmethyl]-isoindole-1,3-dione | HCID 67158056 | — |
| Product | HCID 67157274 | HCID 67157274 | 69% |
Reaction Steps
As described for example 78b, 2-[3-(5-chloro-pyridin-2-yl)-5-methyl-isoxazol-4-ylmethyl]-isoindole-1,3-dione (1.3 g, 3.68 mmol) was converted, instead of 2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethyl]-isoindole-1,3-dione, to the title compound (570 mg, 69%) which was obtained as a white solid. MS: m/e=224.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943619B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-8ed039ca699f488185cd8f2710d0a5e5 |
| Source note | uspto-grants-2011_05 |