Ammonia → HCID 67158185, compound

Participants

Reaction Conditions

Reaction Steps

A Parr vessel was charged with 4-chloro-1-methyl-2-propyl-2H-pyrazolo[3,4-c]quinoline (4.31 g) and a solution of ammonia in methanol (50 mL of 7 N). The reaction was heated at 150° C. for 24 hours and allowed to cool to room temperature. Most of the methanol was removed under reduced pressure, and water was added. A precipitate formed and was isolated by filtration, washed with water, and dried on the vacuum filter funnel to provide 3.8 g of 1-methyl-2-propyl-2H-pyrazolo[3,4-c]quinolin-4-amine as a white solid.

Provenance & Evidence