HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-fluorobenzene-1-sulfonyl chloride → 1-(2-Chloro-4-fluoro-benzenesulfonyl)-4-piperazin-1-yl-1H-pyrrolo[3,2-c]pyridine Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-fluorobenzene-1-sulfonyl chloride | HCID 522846 | — |
| Reactant | 1-Piperazinecarboxylic acid,4-(1h-pyrrolo[3,2-c]pyridin-4-yl)-,1,1-dimethylethyl ester | HCID 67156709 | — |
| Product | 1-(2-Chloro-4-fluoro-benzenesulfonyl)-4-piperazin-1-yl-1H-pyrrolo[3,2-c]pyridine Hydrochloride | HCID 67156863 | — |
Reaction Steps
2-Chloro-4-flourobenzenesulfonyl chloride (29.5 mg) was added to tert-butyl 4-(1H-pyrrolo[3,2-c]pyridin-4-yl)piperazine-1-carboxylate the title compound (2.4 mg). LC/MS RT: 1.361 (System 10 till 40% MeCN over 1.5 min, ACE C8), Purity. 90%. MS: 396 (M+1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943639B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-9b587cdd9cdc48659ff5311b99eedca3 |
| Source note | uspto-grants-2011_05 |