HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chlorothiophene-2-sulfonyl chloride → 1-(5-Chloro-thiophene-2-sulfonyl)-4-piperazin-1-yl-1H-pyrrolo[3,2-c]pyridine Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chlorothiophene-2-sulfonyl chloride | HCID 2733925 | — |
| Reactant | 1-Piperazinecarboxylic acid,4-(1h-pyrrolo[3,2-c]pyridin-4-yl)-,1,1-dimethylethyl ester | HCID 67156709 | — |
| Product | 1-(5-Chloro-thiophene-2-sulfonyl)-4-piperazin-1-yl-1H-pyrrolo[3,2-c]pyridine Hydrochloride | HCID 67157070 | — |
Reaction Steps
5-Chlorothiophene-2-sulfonyl chloride (28.0 mg) was added to tert-butyl 4-(1H-pyrrolo[3,2-c]pyridin-4-yl)piperazine-1-carboxylate the title compound (7.2 mg). LC/MS RT: 1.381 (System 10 till 40% MeCN over 1.5 min, ACE C8), Purity. 97%. MS: 483 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943639B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-c097be5a34dd425a8482371f0ecea297 |
| Source note | uspto-grants-2011_05 |