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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 549346Generated: October 26, 2026

1-Benzyl-2-(bromomethyl)piperidine → (RS)-1-Benzyl-2-[3-(4-fluoro-phenyl)-pyrazol-1-ylmethyl]-piperidine

https://huagongshe.com/reaction/549346

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzyl-2-(bromomethyl)piperidineHCID 23146274—
ReactantHCID 178505519HCID 178505519—
Product(RS)-1-Benzyl-2-[3-(4-fluoro-phenyl)-pyrazol-1-ylmethyl]-piperidineHCID 6715894122.9%

Reaction Steps

The title compound (0.8 g) was prepared from 2-bromomethyl-N-benzylpiperidine (2.68 g) and 3-(4-fluoro-phenyl)-1H-pyrazole (1.62 g) according to the method of example 93.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07943645B2
Source datasetuspto-grants-2011_05
ORD IDord-d0b4690d4f224372956414d06587cb39
Source noteuspto-grants-2011_05