Hydrochloric Acid → HCID 67158972, compound

Participants

Reaction Steps

Following procedures analogous to those described in Example 6 Step b, using concentrated hydrochloric acid (0.5 mL, 6 mmol) in lieu of p-toluenesulfonic acid, 2-[3-(2-methoxy-vinyl)-pyrazolo[1,5-a]pyridin-2-yl]-propan-2-ol (1.23 g, 5.30 mmol) was converted to 1,1-dimethyl-3,4-dihydro-1H-2-oxa-8a,9-diaza-fluoren-3-ol (0.697 g, 3.19 mmol, 60% yield) as a light yellow solid.

Provenance & Evidence