Hydrochloric Acid → HCID 57737264, compound

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Reaction Steps

The solution of 3-{2-[(1H-Pyrrole-2-carbonyl)-amino]-benzoylamino}-thieno[2,3-c]pyrazole-1,5-dicarboxylic acid 5-tert-butyl ester 1-ethyl ester (460.8 mg, 0.88 mmol) in dioxane (10 mL) was treated with HCl 4M in dioxane (10 mL) overnight, the solvent was then removed and the residue was triturated with diethylether (Et2O, 15 mL) yielding 397 mg (96%) of the product, LC-MS: Rt 3.7; [M+H]+ 468;

Provenance & Evidence