反应详情

Following the method of Example 4, 2,6-bis(1,1-dimethylethyl)-4-mercaptophenol (1.19 g, 0.005 mole), the title compound of Example 5 (1.03 g, 0.005 mole) and triethylamine (0.5 ml) were stirred in methanol (100 ml) for 12 hours at room temperature under argon. The solvent and triethylamine were removed on a rotary evaporator and the product purified by chromatography on silica, recrystallized from ethyl aceate/hexane, filtered and dried in vacuo, m.p. ca.172.5°-173.5° C.

1. customThe solvent and triethylamine were removed on a rotary evaporator
2. customthe product purified by chromatography on silica
3. customrecrystallized from ethyl aceate/hexane
4. filtrationfiltered
5. customdried in vacuo, m.p. ca
6. custom172.5°-173.5° C.