HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-[(1R)-2-Amino-1-(hydroxymethyl)-2-oxoethyl]-3-(4-{[4-[5-fluoro-2-(methloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | N-{[3-(4-{[4-[5-Fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)phenyl]carbonyl}-D-serine | HCID 57672647 | — |
| Product | N-[(1R)-2-Amino-1-(hydroxymethyl)-2-oxoethyl]-3-(4-{[4-[5-fluoro-2-(methloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzamide | HCID 24782919 | — |
Reaction Steps
Prepared similarly to Example 14 from N-{[3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)phenyl]carbonyl}-D-serine and ammonia.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943651B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-37b641ffde5041f39dc4c8918c670b7c |
| Source note | uspto-grants-2011_05 |