HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate → HCID 67157181, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate | HCID 7172298 | — |
| Reactant | HCID 86642044 | HCID 86642044 | — |
| Product | HCID 67157181 | HCID 67157181 | — |
Reaction Steps
tert-Butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate (1.00 g) is reacted with triphenyl(3-phenylbutyl)phosphonium iodide (3.53 g) and purified as described in IV-3. This gives tert-butyl 4-{4-[(1Z)-4-phenylpent-1-en-1-yl]-1,3-thiazol-2-yl}piperidine-1-carboxylate (1.23 g) in form of the Z isomer.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07943774B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-a563abe7bb5a4a0b8d3469d4adec5015 |
| Source note | uspto-grants-2011_05 |