Picolyl chloride hydrochloride → HCID 11441018, compound

Participants

Reaction Steps

The title compound was prepared from N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-5 -hydroxypyridine-2-carboxamide and 2-chloromethyl-pyridine hydrochloride according to the method described for Example 4; NMR Spectrum: (DMSOd6) 0.58 (m, 2H), 0.69 (m, 2H), 2.32 (s, 3H), 2.86 (m, 1H), 5.40 (s, 2H), 7.33 (m, 1H), 7.39 (m, 1H), 7.58 (m, 2H), 7.72 (m, 1H), 7.88 (m, 1H), 8.13 (m, 1H), 8.21 (m, 1H), 8.36 (m, 1H), 8.51 (m, 1H), 8.61 (m, 1H), 10.14 (s, 11H); Mass Spectrum: M+H+ 403.

Provenance & Evidence