反应详情

43.4 g (113 mmol) of 2,7-dibromo-9-hydroxy-10,10-dimethyl-9,10-dihydrophenanthrene were suspended in 610 ml of acetic acid. 780 mg of iodine and 3.5 ml of HBr in acetic acid were added, and the suspension was heated to reflux. The mixture was allowed to cool overnight with stirring. The residue was filtered off with suction and washed with water and methanol, giving 35.8 g (87.0% of theory) of the product.

1. temperaturethe suspension was heated to reflux
2. temperatureto cool overnight
3. filtrationThe residue was filtered off with suction
4. washwashed with water and methanol
5. customgiving 35.8 g (87.0% of theory) of the product