HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-{[2-(2-nitrophenyl)ethyl]amino}piperidine-1-carboxylate → Tert-butyl 4-{[2-(2-aminophenyl)ethyl]amino}piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-{[2-(2-nitrophenyl)ethyl]amino}piperidine-1-carboxylate | HCID 18444265 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Tert-butyl 4-{[2-(2-aminophenyl)ethyl]amino}piperidine-1-carboxylate | HCID 18444264 | — |
Reaction Steps
tert-Butyl 4-{[2-(2-nitrophenyl)ethyl]amino}piperidine-1-carboxylate and 10% palladium on carbon (1.9 g) were stirred in ethanol (250 mL) overnight under one atmosphere hydrogen. Catalyst was filtered from the solution and solvent removed in vacuo to provide the title compound (17.2 g). MS: m/z=320 (M+1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07947678B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-636d14fd2da44b0cb1fc941f0dd4ab58 |
| Source note | uspto-grants-2011_05 |