反应详情

To a solution of 5-(4-methyl-5-phenyl-4H-1,2,4-triazol-3-yl)-1-pentanol (127 mg, 0.52 mmol) in DCM (5 ml) was added trietylamine (0.62 mmol) and methansulfonyl chloride (0.57 mmol). The solution was stirred at r.t. for 2 h and quenched with saturated NaHCO3. The organic layer was dried over Na2SO4 and concentrated to give the title compound as light yellow oil (195 mg). MS (m/z): 324[MH]+.

1. customquenched with saturated NaHCO3
2. dry with materialThe organic layer was dried over Na2SO4
3. concentrationconcentrated