2-Amino-4-methylthiazole → HCID 86607490, compound
Reaction equation
CO[C:3]([C:5]1[C:10]([Br:11])=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4].[NH2:12][C:13]1[S:14][CH:15]=[C:16]([CH3:18])[N:17]=1>>[CH3:18][C:16]1[N:17]=[C:13]([NH:12][C:3]([C:5]2[C:10]([Br:11])=[N:9][CH:8]=[CH:7][N:6]=2)=[O:4])[S:14][CH:15]=1Participants
3
Procedure
The title compound, MS: m/e=301.0 (M+H+), was prepared in accordance with the general method of example 1, step 2 from 3-bromo-pyrazine-2-carboxylic acid methyl ester (Example A) and 2-amino-4-methylthiazole.
Sources & evidence
- ORD record
- ord-79d92dd926f64a89812865e36b789209
- Source dataset
- uspto-grants-2011_05
- Patent number
- US07947685B2
Reaction notes
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