2-Amino-4-methylthiazole → HCID 11996466, compound

HRID 550587Notes

Reaction equation

HRID 550587 reaction equation
CO[C:3]([C:5]1[C:10]([NH:11][C:12]2[CH:13]=[N:14][CH:15]=[N:16][CH:17]=2)=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4].[NH2:18][C:19]1[S:20][CH:21]=[C:22]([CH3:24])[N:23]=1>>[CH3:24][C:22]1[N:23]=[C:19]([NH:18][C:3]([C:5]2[C:10]([NH:11][C:12]3[CH:13]=[N:14][CH:15]=[N:16][CH:17]=3)=[N:9][CH:8]=[CH:7][N:6]=2)=[O:4])[S:20][CH:21]=1

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 67151986HCID 67151986, compound

Product 1

HCID 11996466HCID 11996466, compound

Procedure

The title compound, MS: m/e=314.0 (M+H+), was prepared in accordance with the general method of example 1, step 2 from 3-(pyrimidin-5-ylamino)-pyrazine-2-carboxylic acid methyl ester and 2-amino-4-methylthiazole.

Sources & evidence

ORD record
ord-f7015640cba74aca8b4dd037f5a51763
Source dataset
uspto-grants-2011_05
Patent number
US07947685B2

Reaction notes

Loading…