Nitromethane → 2-Methyl-5-(2-nitro-vinyl)-thiophene

HRID 550615Notes

Reaction equation

[CH3:1][C:2]1[S:6][C:5]([CH:7]=O)=[CH:4][CH:3]=1.[N+:9]([CH3:12])([O-:11])=[O:10]>>[CH3:1][C:2]1[S:6][C:5]([CH:7]=[CH:12][N+:9]([O-:11])=[O:10])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 6375Nitromethane

HCID 616635-Methyl-2-thiophenecarboxaldehyde

Product 1

HCID 539158762-Methyl-5-(2-nitro-vinyl)-thiopheneYield 76%

Procedure

In close analogy to the procedure described above, 5-Methyl-thiophene-2-carbaldehyde is reacted with nitromethane to provide the title compound.

Sources & evidence

ORD record: ord-fc39b0f769304bca8773416015018713
Source dataset: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07947689B2

Reaction notes

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