Sodium triacetoxyborohydride → 4-Methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

HRID 550642Notes

Reaction equation

[CH3:1][C:2]1[C:7]2[CH:8]=[CH:9][S:10][C:6]=2[CH2:5][CH2:4][N:3]=1.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>>[CH3:1][CH:2]1[C:7]2[CH:8]=[CH:9][S:10][C:6]=2[CH2:5][CH2:4][NH:3]1

Participants

Reactant 2

HCID 5049666Sodium triacetoxyborohydride

HCID 218211774-methyl-6H,7H-thieno[3,2-c]pyridine

Product 1

HCID 64852954-Methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridineYield 25%

Procedure

In close analogy to the procedure described above, 4-Methyl-6,7-dihydro-thieno[3,2-c]pyridine is reacted with sodium triacetoxyborohydride to provide the title compound.

Sources & evidence

ORD record: ord-a8da3cb06e2d4ac8b08c50ba9bece3e5
Source dataset: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07947689B2

Reaction notes

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