Sodium triacetoxyborohydride → 2,4-Dimethyl-4,5,6,7-tetrahydro-furo[3,2-c]pyridine

HRID 550643Notes

Reaction equation

[CH3:1][C:2]1[O:10][C:9]2[CH2:8][CH2:7][N:6]=[C:5]([CH3:11])[C:4]=2[CH:3]=1.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>>[CH3:1][C:2]1[O:10][C:9]2[CH2:8][CH2:7][NH:6][CH:5]([CH3:11])[C:4]=2[CH:3]=1

Participants

Reactant 2

HCID 5049666Sodium triacetoxyborohydride

HCID 596630682,4-Dimethyl-6,7-dihydro-furo[3,2-c]pyridine

Product 1

HCID 596630922,4-Dimethyl-4,5,6,7-tetrahydro-furo[3,2-c]pyridineYield 45%

Procedure

In close analogy to the procedure described above, 2,4-Dimethyl-6,7-dihydro-furo[3,2-c]pyridine is reacted with sodium triacetoxyborohydride to provide the title compound.

Sources & evidence

ORD record: ord-b60f255e312b4e7c928da5ee3232f9ee
Source dataset: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07947689B2

Reaction notes

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