反应详情

To a solution of 1-methyl-2-thiophen-2-ylethylamine (2 g, 14.2 mmol) in dichloroethane (30 ml) triethylamine (4.3 g, 42.6 mmol) and triphosgene (2.1 g, 7.1 mmol) were added. The reaction mixture stirred for 1 h and concentrated on rotary evaporator. Diethyl ether is added, and the resulting mixture is filtered. Ether solution is concentrated, and the resulting oil is used in the next step without purification.

1. concentrationconcentrated on rotary evaporator
2. additionDiethyl ether is added
3. filtrationthe resulting mixture is filtered
4. concentrationEther solution is concentrated
5. customthe resulting oil is used in the next step without purification