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HRID55067

反应详情

EQUATION

反应方程式

HRID 55067 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1cc(N=C=S)ccc1Cl
HCID520026

4-Chloro-3-(trifluoromethyl)phenyl isothiocyanate

C8H3ClF3NS

结构：COc1ccc2nc(Sc3ccc(N)cc3)ccc2c1
HCID18971662

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc2nc(Sc3ccc(NC(=S)Nc4ccc(Cl)c(C(F)(F)F)c4)cc3)ccc2c1
HCID18971666

未命名化合物

收率 72%

PROCEDURE

实验过程

2-(4-aminophenylthio)-6-methoxyquinoline (15.0 moles, 4.2 g) and 4-chloro-3-trifluoromethylphenylisothiocyanate (15.0 mmoles, 3.6 g) were reacted according to procedure C to yield 5.6 g, 72% of the title compound. Mass Spec (FD) 519. Calculated for C24H17ClF3N3OS2 : C, 55.44; H, 3.30; N, 8.08. Found: C, 55.62; H, 3.43; N, 8.27.